Sandbox Reserved 508: Difference between revisions
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A. Confocal microscope images of cardiomyocytes’ ROS production | A. Confocal microscope images of cardiomyocytes’ ROS production | ||
Top row: ROS in myoctes which have been exposed to adenovirus without the UCP2 protein. Increased DCF fluorescence can be seen over time, representing the presence of a significant level of ROS. Bottom row: ROS in a myocytes exposed to an adenovirus producing the UCP2 protein.DCF fluorescence is barely visible, representing little to no ROS presence. | |||
Top row: ROS in myoctes which have been exposed to adenovirus without the UCP2 protein. Increased DCF fluorescence can be seen over time, representing the presence of a significant level of ROS. | |||
Bottom row: ROS in a myocytes exposed to an adenovirus producing the UCP2 protein. DCF fluorescence is barely visible, representing little to no ROS presence. | |||
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B. Quantitative representation of the changes in ROS levels corresponding to the fluorescence images in A using time-lapse confocal microscopy. The presence of UCP2 greatly reduces ROS levels, limiting damage to cardiac ventricular myocytes. | B. Quantitative representation of the changes in ROS levels corresponding to the fluorescence images in A using time-lapse confocal microscopy. The presence of UCP2 greatly reduces ROS levels, limiting damage to cardiac ventricular myocytes. | ||
