4gev: Difference between revisions

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'''Unreleased structure'''
[[Image:4gev.jpg|left|200px]]


The entry 4gev is ON HOLD
{{STRUCTURE_4gev|  PDB=4gev |  SCENE=  }}


Authors: Newby, Z., Lee, T.T., Finer-Moore, J., Stroud, R.M.
===E. coli thymidylate synthase Y209W variant in complex with substrate and a cofactor analog===


Description: E. coli thymidylate synthase Y209W variant in complex with substrate and a cofactor analog
{{ABSTRACT_PUBMED_16768437}}
 
==About this Structure==
[[4gev]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2g8m 2g8m]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GEV OCA].  
 
==Reference==
<ref group="xtra">PMID:016768437</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Thymidylate synthase]]
[[Category: Finer-Moore, J.]]
[[Category: Lee, T T.]]
[[Category: Newby, Z.]]
[[Category: Stroud, R M.]]
[[Category: Alpha/beta protein]]
[[Category: Beta sheet]]
[[Category: Methylase]]
[[Category: Transferase]]

Revision as of 05:02, 29 August 2012

File:4gev.jpg

Template:STRUCTURE 4gev

E. coli thymidylate synthase Y209W variant in complex with substrate and a cofactor analog

Template:ABSTRACT PUBMED 16768437

About this Structure

4gev is a 2 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 2g8m. Full crystallographic information is available from OCA.

Reference

  1. Newby Z, Lee TT, Morse RJ, Liu Y, Liu L, Venkatraman P, Santi DV, Finer-Moore JS, Stroud RM. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 2006 Jun 20;45(24):7415-28. PMID:16768437 doi:10.1021/bi060152s

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