1i7m: Difference between revisions

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[[Image:1i7m.gif|left|200px]]~~<br /><applet load~~="1i7m~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:1i7m.gif|left|200px]]

~~caption="~~1i7m, resolution 2.24Å" />

'''HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COMPLEXED WITH 4-AMIDINOINDAN-1-ONE-2'-AMIDINOHYDRAZONE'''~~<br />~~

{{Structure

|PDB= 1i7m |SIZE=350|CAPTION= <scene name='initialview01'>1i7m</scene>, resolution 2.24Å

|SITE=

|LIGAND= <scene name='pdbligand=PUT:1,4-DIAMINOBUTANE'>PUT</scene> and <scene name='pdbligand=CG:4-AMIDINOINDAN-1-ONE-2'-AMIDINOHYDRAZONE'>CG</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Adenosylmethionine_decarboxylase Adenosylmethionine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.50 4.1.1.50]

|GENE=

}}

'''HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COMPLEXED WITH 4-AMIDINOINDAN-1-ONE-2'-AMIDINOHYDRAZONE'''

==Overview==

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==About this Structure==

1I7M is a [~~http://en.wikipedia.org/wiki/Protein_complex~~ Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=PUT:'>PUT</scene> and <scene name='pdbligand=CG:'>CG</scene> as [http://en.wikipedia.org/wiki/ligands ligands~~]. ~~Active as [http://en.wikipedia.org/wiki/Adenosylmethionine_decarboxylase Adenosylmethionine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.50 4.1.1.50]~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I7M OCA].

1I7M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I7M OCA].

==Reference==

The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase., Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE, Biochemistry. 2001 Aug 14;40(32):9484-94. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~11583147 11583147]

The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase., Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE, Biochemistry. 2001 Aug 14;40(32):9484-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11583147 11583147]

[[Category: Adenosylmethionine decarboxylase]]

[[Category: Homo sapiens]]

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[[Category: spermidine biosynthesis]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 13~~:08:50 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:46:35 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1i7m.gif|left|200px]]<br /><applet load="1i7m" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1i7m.gif|left|200px]]
-caption="1i7m, resolution 2.24&Aring;" />
-'''HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COMPLEXED WITH 4-AMIDINOINDAN-1-ONE-2'-AMIDINOHYDRAZONE'''<br />
+ {{Structure
+|PDB= 1i7m |SIZE=350|CAPTION= <scene name='initialview01'>1i7m</scene>, resolution 2.24&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=PUT:1,4-DIAMINOBUTANE'>PUT</scene> and <scene name='pdbligand=CG:4-AMIDINOINDAN-1-ONE-2'-AMIDINOHYDRAZONE'>CG</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Adenosylmethionine_decarboxylase Adenosylmethionine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.50 4.1.1.50]
+|GENE=
+}}
+'''HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COMPLEXED WITH 4-AMIDINOINDAN-1-ONE-2'-AMIDINOHYDRAZONE'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-I7M is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PUT:'>PUT</scene> and <scene name='pdbligand=CG:'>CG</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenosylmethionine_decarboxylase Adenosylmethionine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.50 4.1.1.50] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I7M OCA].
+I7M is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I7M OCA].
 ==Reference==
-The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase., Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE, Biochemistry. 2001 Aug 14;40(32):9484-94. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11583147 11583147]
+The structural basis for substrate specificity and inhibition of human S-adenosylmethionine decarboxylase., Tolbert WD, Ekstrom JL, Mathews II, Secrist JA 3rd, Kapoor P, Pegg AE, Ealick SE, Biochemistry. 2001 Aug 14;40(32):9484-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11583147 11583147]
 [[Category: Adenosylmethionine decarboxylase]]
 [[Category: Homo sapiens]]
@@ Line 34: / Line 43: @@
 [[Category: spermidine biosynthesis]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:08:50 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:46:35 2008''