Defensin: Difference between revisions
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Michal Harel (talk | contribs) New page: == Your Heading Here (maybe something like 'Structure') == <StructureSection load='1dq8' size='350' side='right' caption='Structure of HMG-CoA reductase (PDB entry 1dq8)' scene=''> Any... |
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== | {{STRUCTURE_2kht| PDB=2kht | SIZE=400| SCENE= |right|CAPTION=Human α-defensin 1, [[2kht]] }} | ||
'''Defensins''' (DEF) are small cationic defense proteins active against bacteria, fungi and viruses. DEF contains 6-8 conserved cysteine residues. DEF binds to microbial cell membrane forming pores and thus allowing outflow of essential nutrients. There is increase in α-DEF in chronic inflammations and several cancers. For details on plant DEF see [[Plant defensing]]. | '''Defensins''' (DEF) are small cationic defense proteins active against bacteria, fungi and viruses. DEF contains 6-8 conserved cysteine residues. DEF binds to microbial cell membrane forming pores and thus allowing outflow of essential nutrients. There is increase in α-DEF in chronic inflammations and several cancers. For details on plant DEF see [[Plant defensing]]. | ||
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[[1zmh]], [[1zmi]], [[1zmk]] - hDEFA HNP-2 (mutant) – human<BR /> | [[1zmh]], [[1zmi]], [[1zmk]] - hDEFA HNP-2 (mutant) – human<BR /> | ||
[[3gny]], [[3go0]], [[3hj2]] - hDEFA HNP-1<BR /> | [[3gny]], [[3go0]], [[3hj2]] - hDEFA HNP-1<BR /> | ||
[[2kht]] - hDEFA HNP-1 | [[2kht]] - hDEFA HNP-1 - NMR<BR /> | ||
[[2pm1]], [[2pm4]], [[2pm5]], [[3hjd]], [[3h6c]], [[3lo1]], [[3lo2]], [[3lo4]], [[3lo6]], [[3lo8]], [[3loe]], [[3lvx]], [[4du0]] - hDEFA HNP-1 (mutant) <BR /> | [[2pm1]], [[2pm4]], [[2pm5]], [[3hjd]], [[3h6c]], [[3lo1]], [[3lo2]], [[3lo4]], [[3lo6]], [[3lo8]], [[3loe]], [[3lvx]], [[4du0]] - hDEFA HNP-1 (mutant) <BR /> | ||
[[1zmm]] – hDEFA4 <BR /> | [[1zmm]] – hDEFA4 <BR /> | ||
