1ih0: Difference between revisions

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[[Image:1ih0.jpg|left|200px]]<br /><~~applet load~~=~~"1ih0" size~~=~~"350" color~~=~~"white" frame~~=~~"true" align~~=~~"right" spinBox="true"~~

[[Image:1ih0.jpg|left|200px]]

~~caption~~=~~"1ih0"~~ />

'''Structure of the C-domain of Human Cardiac Troponin C in Complex with Ca2+ Sensitizer EMD 57033'''~~<br />~~

{{Structure

|PDB= 1ih0 |SIZE=350|CAPTION= <scene name='initialview01'>1ih0</scene>

|SITE=

|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=EMD:5-[1-(3,4-DIMETHOXY-BENZOYL)-1,2,3,4-TETRAHYDRO-QUINOLIN-6-YL]-6-METHYL-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-ONE'>EMD</scene>

|ACTIVITY=

|GENE= cTnC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])

}}

'''Structure of the C-domain of Human Cardiac Troponin C in Complex with Ca2+ Sensitizer EMD 57033'''

==Overview==

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==Disease==

Known diseases associated with this structure: Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]]

Known diseases associated with this structure: Cardiomyopathy, dilated, 1Z OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]], Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]]

==About this Structure==

1IH0 is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens~~] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=EMD:'>EMD</scene> as [http://en.wikipedia.org/wiki/ligands ligands~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH0 OCA].

1IH0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH0 OCA].

==Reference==

Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033., Wang X, Li MX, Spyracopoulos L, Beier N, Chandra M, Solaro RJ, Sykes BD, J Biol Chem. 2001 Jul 6;276(27):25456-66. Epub 2001 Apr 24. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~11320096 11320096]

Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033., Wang X, Li MX, Spyracopoulos L, Beier N, Chandra M, Solaro RJ, Sykes BD, J Biol Chem. 2001 Jul 6;276(27):25456-66. Epub 2001 Apr 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11320096 11320096]

[[Category: Homo sapiens]]

[[Category: Single protein]]

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[[Category: ca2+ sensitizer]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 13~~:11:48 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:50:20 2008''

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@@ Line 1: / Line 1: @@
-[[Image:1ih0.jpg|left|200px]]<br /><applet load="1ih0" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1ih0.jpg|left|200px]]
-caption="1ih0" />
-'''Structure of the C-domain of Human Cardiac Troponin C in Complex with Ca2+ Sensitizer EMD 57033'''<br />
+ {{Structure
+|PDB= 1ih0 |SIZE=350|CAPTION= <scene name='initialview01'>1ih0</scene>
+|SITE=
+|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=EMD:5-[1-(3,4-DIMETHOXY-BENZOYL)-1,2,3,4-TETRAHYDRO-QUINOLIN-6-YL]-6-METHYL-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-ONE'>EMD</scene>
+|ACTIVITY=
+|GENE= cTnC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Structure of the C-domain of Human Cardiac Troponin C in Complex with Ca2+ Sensitizer EMD 57033'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==Disease==
-Known diseases associated with this structure: Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]]
+Known diseases associated with this structure: Cardiomyopathy, dilated, 1Z OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]], Cardiomyopathy, familial hypertrophic, 192600 (3) OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=191040 191040]]
 ==About this Structure==
-IH0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=EMD:'>EMD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH0 OCA].
+IH0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IH0 OCA].
 ==Reference==
-Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033., Wang X, Li MX, Spyracopoulos L, Beier N, Chandra M, Solaro RJ, Sykes BD, J Biol Chem. 2001 Jul 6;276(27):25456-66. Epub 2001 Apr 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11320096 11320096]
+Structure of the C-domain of human cardiac troponin C in complex with the Ca2+ sensitizing drug EMD 57033., Wang X, Li MX, Spyracopoulos L, Beier N, Chandra M, Solaro RJ, Sykes BD, J Biol Chem. 2001 Jul 6;276(27):25456-66. Epub 2001 Apr 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11320096 11320096]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
@@ Line 28: / Line 37: @@
 [[Category: ca2+ sensitizer]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:11:48 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:50:20 2008''