1il0: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
Line 1: Line 1:
[[Image:1il0.jpg|left|200px]]<br /><applet load="1il0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1il0.jpg|left|200px]]
caption="1il0, resolution 2.20&Aring;" />
 
'''X-RAY CRYSTAL STRUCTURE OF THE E170Q MUTANT OF HUMAN L-3-HYDROXYACYL-COA DEHYDROGENASE'''<br />
{{Structure
|PDB= 1il0 |SIZE=350|CAPTION= <scene name='initialview01'>1il0</scene>, resolution 2.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CAA:ACETOACETYL-COENZYME+A'>CAA</scene> and <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-hydroxyacyl-CoA_dehydrogenase 3-hydroxyacyl-CoA dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.35 1.1.1.35]
|GENE= HCDH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''X-RAY CRYSTAL STRUCTURE OF THE E170Q MUTANT OF HUMAN L-3-HYDROXYACYL-COA DEHYDROGENASE'''
 


==Overview==
==Overview==
Line 10: Line 19:


==About this Structure==
==About this Structure==
1IL0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CAA:'>CAA</scene> and <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-hydroxyacyl-CoA_dehydrogenase 3-hydroxyacyl-CoA dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.35 1.1.1.35] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IL0 OCA].  
1IL0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IL0 OCA].  


==Reference==
==Reference==
Glutamate 170 of human l-3-hydroxyacyl-CoA dehydrogenase is required for proper orientation of the catalytic histidine and structural integrity of the enzyme., Barycki JJ, O'Brien LK, Strauss AW, Banaszak LJ, J Biol Chem. 2001 Sep 28;276(39):36718-26. Epub 2001 Jul 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11451959 11451959]
Glutamate 170 of human l-3-hydroxyacyl-CoA dehydrogenase is required for proper orientation of the catalytic histidine and structural integrity of the enzyme., Barycki JJ, O'Brien LK, Strauss AW, Banaszak LJ, J Biol Chem. 2001 Sep 28;276(39):36718-26. Epub 2001 Jul 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11451959 11451959]
[[Category: 3-hydroxyacyl-CoA dehydrogenase]]
[[Category: 3-hydroxyacyl-CoA dehydrogenase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 25: Line 34:
[[Category: abortive ternary complex]]
[[Category: abortive ternary complex]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:13:01 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:51:48 2008''
Retrieved from "https://proteopedia.org/1il0"