1inf: Difference between revisions

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[[Image:1inf.jpg|left|200px]]<br /><applet load="1inf" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1inf.jpg|left|200px]]
caption="1inf, resolution 2.4&Aring;" />
 
'''INFLUENZA VIRUS B/LEE/40 NEURAMINIDASE COMPLEXED WITH BANA113 INHIBITOR'''<br />
{{Structure
|PDB= 1inf |SIZE=350|CAPTION= <scene name='initialview01'>1inf</scene>, resolution 2.4&Aring;
|SITE= <scene name='pdbsite=CAT:Substrate+(Sialic+Acid)+Binding+Residues+Catalytic+Site'>CAT</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene> and <scene name='pdbligand=ST4:4-(ACETYLAMINO)-3-GUANIDINOBENZOIC ACID'>ST4</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18]
|GENE=
}}
 
'''INFLUENZA VIRUS B/LEE/40 NEURAMINIDASE COMPLEXED WITH BANA113 INHIBITOR'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1INF is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Influenza_b_virus Influenza b virus] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=CA:'>CA</scene> and <scene name='pdbligand=ST4:'>ST4</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] Known structural/functional Site: <scene name='pdbsite=CAT:Substrate+(Sialic+Acid)+Binding+Residues+Catalytic+Site'>CAT</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1INF OCA].  
1INF is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Influenza_b_virus Influenza b virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1INF OCA].  


==Reference==
==Reference==
Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction., Singh S, Jedrzejas MJ, Air GM, Luo M, Laver WG, Brouillette WJ, J Med Chem. 1995 Aug 18;38(17):3217-25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7650674 7650674]
Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction., Singh S, Jedrzejas MJ, Air GM, Luo M, Laver WG, Brouillette WJ, J Med Chem. 1995 Aug 18;38(17):3217-25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7650674 7650674]
[[Category: Exo-alpha-sialidase]]
[[Category: Exo-alpha-sialidase]]
[[Category: Influenza b virus]]
[[Category: Influenza b virus]]
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[[Category: sialidase]]
[[Category: sialidase]]


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