1is0: Difference between revisions

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[[Image:1is0.jpg|left|200px]]<br /><applet load="1is0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1is0.jpg|left|200px]]
caption="1is0, resolution 1.90&Aring;" />
 
'''Crystal Structure of a Complex of the Src SH2 Domain with Conformationally Constrained Peptide Inhibitor'''<br />
{{Structure
|PDB= 1is0 |SIZE=350|CAPTION= <scene name='initialview01'>1is0</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PTC:2-METHYLCARBAMOYL-3-(4-PHOSPHONOOXY-PHENYL)-CYCLOPROPANECARBOXYLIC ACID'>PTC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE=
}}
 
'''Crystal Structure of a Complex of the Src SH2 Domain with Conformationally Constrained Peptide Inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1IS0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus] with <scene name='pdbligand=PTC:'>PTC</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IS0 OCA].  
1IS0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IS0 OCA].  


==Reference==
==Reference==
Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding., Davidson JP, Lubman O, Rose T, Waksman G, Martin SF, J Am Chem Soc. 2002 Jan 16;124(2):205-15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11782172 11782172]
Calorimetric and structural studies of 1,2,3-trisubstituted cyclopropanes as conformationally constrained peptide inhibitors of Src SH2 domain binding., Davidson JP, Lubman O, Rose T, Waksman G, Martin SF, J Am Chem Soc. 2002 Jan 16;124(2):205-15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11782172 11782172]
[[Category: Rous sarcoma virus]]
[[Category: Rous sarcoma virus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: conformationaly constrained]]
[[Category: conformationaly constrained]]


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