1iwa: Difference between revisions
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[[Image:1iwa.gif|left|200px]] | [[Image:1iwa.gif|left|200px]] | ||
'''RUBISCO FROM GALDIERIA PARTITA''' | {{Structure | ||
|PDB= 1iwa |SIZE=350|CAPTION= <scene name='initialview01'>1iwa</scene>, resolution 2.60Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Ribulose-bisphosphate_carboxylase Ribulose-bisphosphate carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.39 4.1.1.39] | |||
|GENE= | |||
}} | |||
'''RUBISCO FROM GALDIERIA PARTITA''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1IWA is a [ | 1IWA is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Galdieria_partita Galdieria partita]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWA OCA]. | ||
==Reference== | ==Reference== | ||
X-ray structure of Galdieria Rubisco complexed with one sulfate ion per active site., Okano Y, Mizohata E, Xie Y, Matsumura H, Sugawara H, Inoue T, Yokota A, Kai Y, FEBS Lett. 2002 Sep 11;527(1-3):33-6. PMID:[http:// | X-ray structure of Galdieria Rubisco complexed with one sulfate ion per active site., Okano Y, Mizohata E, Xie Y, Matsumura H, Sugawara H, Inoue T, Yokota A, Kai Y, FEBS Lett. 2002 Sep 11;527(1-3):33-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12220629 12220629] | ||
[[Category: Galdieria partita]] | [[Category: Galdieria partita]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: rubisco]] | [[Category: rubisco]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 11:55:47 2008'' | ||
Revision as of 09:55, 20 March 2008
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| 1iwa, resolution 2.60Å | |||||||||||||
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| Ligands: | SO4 | ||||||||||||
| Activity: | Ribulose-bisphosphate carboxylase, with EC number 4.1.1.39 | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
RUBISCO FROM GALDIERIA PARTITA
Overview
Ribulose-1,5-bisphosphate carboxylase/oxygenase (Rubisco) catalyzes the reactions of carboxylation and oxygenation of ribulose-1,5-bisphosphate. These reactions require that the active site should be closed by a flexible loop (loop 6) of the large subunit. Rubisco from a red alga, Galdieria partita, has the highest specificity for carboxylation reaction among the Rubiscos hitherto reported. The crystal structure of unactivated Galdieria Rubisco has been determined at 2.6 A resolution. The electron density map reveals that a sulfate binds only to the P1 anion-binding site of the active site and the loop 6 is closed. Galdieria Rubisco has a unique hydrogen bond between the main chain oxygen of Val332 on the loop 6 and the epsilon-amino group of Gln386 of the same large subunit. This interaction is likely to be crucial to understanding for stabilizing the loop 6 in the closed state and to making a higher affinity for anionic ligands.
About this Structure
1IWA is a Protein complex structure of sequences from Galdieria partita. Full crystallographic information is available from OCA.
Reference
X-ray structure of Galdieria Rubisco complexed with one sulfate ion per active site., Okano Y, Mizohata E, Xie Y, Matsumura H, Sugawara H, Inoue T, Yokota A, Kai Y, FEBS Lett. 2002 Sep 11;527(1-3):33-6. PMID:12220629
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