1qks: Difference between revisions
New page: left|200px<br /> <applet load="1qks" size="450" color="white" frame="true" align="right" spinBox="true" caption="1qks, resolution 1.28Å" /> '''CYTOCHROME CD1 NITR... |
No edit summary |
||
| Line 8: | Line 8: | ||
==About this Structure== | ==About this Structure== | ||
1QKS is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans]] with SO4, HEC, DHE and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QKS OCA]]. | 1QKS is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Paracoccus_denitrificans Paracoccus denitrificans]] with SO4, HEC, DHE and GOL as [[http://en.wikipedia.org/wiki/ligands ligands]]. Structure known Active Sites: C1A, C1B, D1A and D1B. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1QKS OCA]]. | ||
==Reference== | ==Reference== | ||
| Line 26: | Line 26: | ||
[[Category: periplasmic]] | [[Category: periplasmic]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 08:31:01 2007'' | ||
Revision as of 06:26, 30 October 2007
|
CYTOCHROME CD1 NITRITE REDUCTASE, OXIDISED FORM
Overview
Cytochrome cd1-nitrite reductase is a bifunctional enzyme that catalyzes, the one-electron reduction of nitrite to nitric oxide and the, four-electron reduction of oxygen to water. The 1.55 A crystal structure, of the dimeric enzyme from Thiosphaera pantotropha is reported here. The, protein was sequenced from the X-ray structure. Each subunit contains a, covalent c heme with two axial His ligands (His-17, His-69) and a unique, noncovalent d1 heme ligated by Tyr-25 and His-200. The d1 heme is the, mononuclear iron center where both oxygen and nitrite reduction take, place. The two types of heme are located in separate domains whose, arrangement suggests a mechanism requiring domain movement during, catalysis.
About this Structure
1QKS is a [Single protein] structure of sequence from [Paracoccus denitrificans] with SO4, HEC, DHE and GOL as [ligands]. Structure known Active Sites: C1A, C1B, D1A and D1B. Full crystallographic information is available from [OCA].
Reference
The anatomy of a bifunctional enzyme: structural basis for reduction of oxygen to water and synthesis of nitric oxide by cytochrome cd1., Fulop V, Moir JW, Ferguson SJ, Hajdu J, Cell. 1995 May 5;81(3):369-77. PMID:7736589
Page seeded by OCA on Tue Oct 30 08:31:01 2007
