StudioG24SecL04Tpc5: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Tasfik Ahmed (talk | contribs) No edit summary |
Tasfik Ahmed (talk | contribs) No edit summary |
||
| Line 5: | Line 5: | ||
==VlsE== | ==VlsE== | ||
The causative agent of [http://en.wikipedia.org/wiki/Lyme_disease Lyme Disease], a multi-stage infection, is a family of spirochetes found in the guts of Ixodes ticks. The Variable Major Protein (VMP)-like sequence Expressed (VlsE) is the specific outer-surface lipoprotein that enables the spirochete to evade immune response through mechanisms of [http://en.wikipedia.org/wiki/Antigenic_variation antigenic variation]. In addition to inducing a strong immune response in the host, VlsE is useful in the serodiagnosis of Lyme disease. | The causative agent of [http://en.wikipedia.org/wiki/Lyme_disease Lyme Disease], a multi-stage infection, is a family of spirochetes found in the guts of Ixodes ticks. The Variable Major Protein (VMP)-like sequence Expressed (VlsE) is the specific outer-surface lipoprotein that enables the spirochete to evade immune response through mechanisms of [http://en.wikipedia.org/wiki/Antigenic_variation antigenic variation]. In addition to inducing a strong immune response in the host, VlsE is useful in the serodiagnosis of Lyme disease. | ||
| Line 17: | Line 17: | ||
===Invariable=== | ===Invariable=== | ||
Invariable Region:<scene name='StudioG24SecL04Tpc5/Invariable_regions/1'>IR</scene> | |||
==Antigenicity== | ==Antigenicity== | ||
<Structure load='1l8w' size='300' frame='true' align='right' caption='IR6:Immunodominate Region of VlsE' scene='StudioG24SecL04Tpc5/Ir6_highlight/3' /> | |||
==Function in Immune System Evasion== | ==Function in Immune System Evasion== | ||
