G04SecL04Tpc1: Difference between revisions
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===Osp-B H6831 complex=== | ===Osp-B H6831 complex=== | ||
In its original form,Outer Surface Protein B has 12 Beta sheets. However, a <scene name='G04SecL04Tpc1/Osp_b_fab_complex/1'>truncated form of Osp-B</scene>, purple, is displayed in the complex formed when the C-terminus of Osp B binds to the antibody H6831. The Osp B binds to the Fab <scene name='G04SecL04Tpc1/L_chain/1'> light chain</scene> and <scene name='G04SecL04Tpc1/H_chain/1'>heavy chain</scene>regions of the H6831. | |||
There are <scene name='G04SecL04Tpc1/Osp_b_fab_complex/8'>three loop regions</scene> on the c-terminal Osp-B that interact with the Fab of H6831. The major interactions of the complex occur between loop region two, seen in pink, and the Fab heavy chain. More minor hydrogen bonding interactions occur between loop one,green, and the heavy chain as well as loop three,orange, and the light chains | There are <scene name='G04SecL04Tpc1/Osp_b_fab_complex/8'>three loop regions</scene> on the c-terminal Osp-B that interact with the Fab of H6831. The major interactions of the complex occur between loop region two, seen in pink, and the Fab heavy chain. More minor hydrogen bonding interactions occur between loop one,green, and the heavy chain as well as loop three,orange, and the light chains | ||