4geb: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4geb|  PDB=4geb  |  SCENE=  }}
===Kynurenine Aminotransferase II Inhibitors===
{{ABSTRACT_PUBMED_23466229}}


The entry 4geb is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/AADAT_HUMAN AADAT_HUMAN]] Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro).<ref>PMID:18620547</ref>  


Authors: Pandit, J.
==About this Structure==
[[4geb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GEB OCA].  


Description: Kynurenine Aminotransferase II Inhibitors
==Reference==
<ref group="xtra">PMID:023466229</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Pandit, J.]]
[[Category: Aminotransferase]]
[[Category: Irreversible inhibitor]]
[[Category: Transferase-transferase inhibitor complex]]