4gev: Difference between revisions
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[[Image:4gev. | [[Image:4gev.png|left|200px]] | ||
{{STRUCTURE_4gev| PDB=4gev | SCENE= }} | {{STRUCTURE_4gev| PDB=4gev | SCENE= }} | ||
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===E. coli thymidylate synthase Y209W variant in complex with substrate and a cofactor analog=== | ===E. coli thymidylate synthase Y209W variant in complex with substrate and a cofactor analog=== | ||
{{ | {{ABSTRACT_PUBMED_23034004}} | ||
==About this Structure== | ==About this Structure== | ||
[[4gev]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[4gev]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2g8m 2g8m]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GEV OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:016768437</ref><references group="xtra"/> | <ref group="xtra">PMID:016768437</ref><references group="xtra"/> | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli k-12]] | ||
[[Category: Thymidylate synthase]] | [[Category: Thymidylate synthase]] | ||
[[Category: Finer-Moore, J.]] | [[Category: Finer-Moore, J.]] | ||
Revision as of 05:57, 17 October 2012
E. coli thymidylate synthase Y209W variant in complex with substrate and a cofactor analog
Template:ABSTRACT PUBMED 23034004
About this Structure
4gev is a 2 chain structure with sequence from Escherichia coli k-12. This structure supersedes the now removed PDB entry 2g8m. Full crystallographic information is available from OCA.
Reference
- Newby Z, Lee TT, Morse RJ, Liu Y, Liu L, Venkatraman P, Santi DV, Finer-Moore JS, Stroud RM. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 2006 Jun 20;45(24):7415-28. PMID:16768437 doi:10.1021/bi060152s