1jf7: Difference between revisions

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[[Image:1jf7.gif|left|200px]]<br /><applet load="1jf7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1jf7.gif|left|200px]]
caption="1jf7, resolution 2.20&Aring;" />
 
'''HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH PNU177836'''<br />
{{Structure
|PDB= 1jf7 |SIZE=350|CAPTION= <scene name='initialview01'>1jf7</scene>, resolution 2.20&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=TBH:5-(2-{2-[(TERT-BUTOXY-HYDROXY-METHYL)-AMINO]-1-HYDROXY-3-PHENYL-PROPYLAMINO}-3-HYDROXY-3-PENTYLAMINO-PROPYL)-2-CARBOXYMETHOXY-BENZOIC ACID'>TBH</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]
|GENE=
}}
 
'''HUMAN PTP1B CATALYTIC DOMAIN COMPLEXED WITH PNU177836'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1JF7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=TBH:'>TBH</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JF7 OCA].  
1JF7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JF7 OCA].  


==Reference==
==Reference==
Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B., Larsen SD, Barf T, Liljebris C, May PD, Ogg D, O'Sullivan TJ, Palazuk BJ, Schostarez HJ, Stevens FC, Bleasdale JE, J Med Chem. 2002 Jan 31;45(3):598-622. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11806712 11806712]
Synthesis and biological activity of a novel class of small molecular weight peptidomimetic competitive inhibitors of protein tyrosine phosphatase 1B., Larsen SD, Barf T, Liljebris C, May PD, Ogg D, O'Sullivan TJ, Palazuk BJ, Schostarez HJ, Stevens FC, Bleasdale JE, J Med Chem. 2002 Jan 31;45(3):598-622. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11806712 11806712]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
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[[Category: tyrosine phosphatase]]
[[Category: tyrosine phosphatase]]


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