1jr1: Difference between revisions

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[[Image:1jr1.jpg|left|200px]]<br /><applet load="1jr1" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1jr1.jpg|left|200px]]
caption="1jr1, resolution 2.6&Aring;" />
 
'''Crystal structure of Inosine Monophosphate Dehydrogenase in complex with Mycophenolic Acid'''<br />
{{Structure
|PDB= 1jr1 |SIZE=350|CAPTION= <scene name='initialview01'>1jr1</scene>, resolution 2.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene> and <scene name='pdbligand=MOA:MYCOPHENOLIC ACID'>MOA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205]
|GENE=
}}
 
'''Crystal structure of Inosine Monophosphate Dehydrogenase in complex with Mycophenolic Acid'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1JR1 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus] with <scene name='pdbligand=K:'>K</scene>, <scene name='pdbligand=IMP:'>IMP</scene> and <scene name='pdbligand=MOA:'>MOA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JR1 OCA].  
1JR1 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Cricetulus_griseus Cricetulus griseus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JR1 OCA].  


==Reference==
==Reference==
Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid., Sintchak MD, Fleming MA, Futer O, Raybuck SA, Chambers SP, Caron PR, Murcko MA, Wilson KP, Cell. 1996 Jun 14;85(6):921-30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=8681386 8681386]
Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid., Sintchak MD, Fleming MA, Futer O, Raybuck SA, Chambers SP, Caron PR, Murcko MA, Wilson KP, Cell. 1996 Jun 14;85(6):921-30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8681386 8681386]
[[Category: Cricetulus griseus]]
[[Category: Cricetulus griseus]]
[[Category: IMP dehydrogenase]]
[[Category: IMP dehydrogenase]]
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[[Category: mycophenolic acid]]
[[Category: mycophenolic acid]]


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