4gcy: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4gcy| PDB=4gcy | SCENE= }} | |||
===Structure of Mycobacterium tuberculosis dUTPase H21W mutant=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DUT_MYCTU DUT_MYCTU]] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[HAMAP-Rule:MF_00116] | |||
==About this Structure== | |||
[[4gcy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCY OCA]. | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: DUTP diphosphatase]] | |||
[[Category: Bendes, A.]] | |||
[[Category: Leveles, I.]] | |||
[[Category: Toth, J.]] | |||
[[Category: Vertessy, B G.]] | |||
[[Category: Hydrolase]] | |||
[[Category: Jelly-roll]] | |||
Revision as of 14:16, 3 July 2013
Structure of Mycobacterium tuberculosis dUTPase H21W mutant
Function
[DUT_MYCTU] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.[HAMAP-Rule:MF_00116]
About this Structure
4gcy is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
