4guo: Difference between revisions
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{{STRUCTURE_4guo| PDB=4guo | SCENE= }} | |||
===structure of p73 DNA binding domain complex with 12 bp DNA=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref> | |||
==About this Structure== | |||
[[4guo]] is a 16 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GUO OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Ethayathulla, A S]] | |||
[[Category: Viadiu, H.]] | |||
[[Category: Beta-immunoglobulin fold]] | |||
[[Category: Dna]] | |||
[[Category: Dna binding]] | |||
[[Category: Transcription factor]] | |||
[[Category: Transcription-dna complex]] | |||
[[Category: Tumor suppressor]] | |||