4gme: Difference between revisions
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==Crystal structure of mannonate dehydratase (target EFI-502209) from caulobacter crescentus cb15 complexed with magnesium and d-mannonate== | |||
<StructureSection load='4gme' size='340' side='right' caption='[[4gme]], [[Resolution|resolution]] 2.00Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4gme]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GME OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GME FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=CS2:D-MANNONIC+ACID'>CS2</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CC_0532 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=155892 Caulobacter vibrioides])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gme FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gme OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gme RCSB], [http://www.ebi.ac.uk/pdbsum/4gme PDBsum]</span></td></tr> | |||
== | </table> | ||
[[4gme]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Caulobacter_vibrioides Caulobacter vibrioides]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GME OCA]. | == Function == | ||
[[http://www.uniprot.org/uniprot/Q9AAR4_CAUCR Q9AAR4_CAUCR]] Catalyzes the dehydration of D-mannonate. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Caulobacter vibrioides]] | [[Category: Caulobacter vibrioides]] | ||
[[Category: Almo, S C | [[Category: Almo, S C]] | ||
[[Category: Bhosle, R | [[Category: Bhosle, R]] | ||
[[Category: Chowdhury, S | [[Category: Chowdhury, S]] | ||
[[Category: EFI, Enzyme Function Initiative | [[Category: EFI, Enzyme Function Initiative]] | ||
[[Category: Evans, B | [[Category: Evans, B]] | ||
[[Category: Gerlt, J A | [[Category: Gerlt, J A]] | ||
[[Category: Glenn, A Scott | [[Category: Glenn, A Scott]] | ||
[[Category: Hammonds, J | [[Category: Hammonds, J]] | ||
[[Category: Hillerich, B | [[Category: Hillerich, B]] | ||
[[Category: Imker, H J | [[Category: Imker, H J]] | ||
[[Category: Patskovsky, Y | [[Category: Patskovsky, Y]] | ||
[[Category: Seidel, R D | [[Category: Seidel, R D]] | ||
[[Category: Toro, R | [[Category: Toro, R]] | ||
[[Category: Washington, E | [[Category: Washington, E]] | ||
[[Category: Zencheck, W D | [[Category: Zencheck, W D]] | ||
[[Category: Efi]] | [[Category: Efi]] | ||
[[Category: Enolase]] | [[Category: Enolase]] | ||