4gfk: Difference between revisions
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{{STRUCTURE_4gfk| PDB=4gfk | SCENE= }} | |||
===structures of NO factors=== | |||
{{ABSTRACT_PUBMED_23754405}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/SLMA_VIBCH SLMA_VIBCH]] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity). | |||
==About this Structure== | |||
[[4gfk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o1_biovar_el_tor_str._n16961 Vibrio cholerae o1 biovar el tor str. n16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFK OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023754405</ref><references group="xtra"/><references/> | |||
[[Category: Vibrio cholerae o1 biovar el tor str. n16961]] | |||
[[Category: Schumacher, M A.]] | |||
[[Category: Dna binding protein]] | |||
[[Category: Ftsz]] | |||
[[Category: No]] | |||
[[Category: Nucleoid occlusion]] | |||
[[Category: Slma]] | |||
[[Category: Tetr family]] | |||
Revision as of 13:57, 19 June 2013
structures of NO factors
Template:ABSTRACT PUBMED 23754405
Function
[SLMA_VIBCH] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity).
About this Structure
4gfk is a 2 chain structure with sequence from Vibrio cholerae o1 biovar el tor str. n16961. Full crystallographic information is available from OCA.
Reference
- Tonthat NK, Milam SL, Chinnam N, Whitfill T, Margolin W, Schumacher MA. SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid. Proc Natl Acad Sci U S A. 2013 Jun 10. PMID:23754405 doi:10.1073/pnas.1221036110
