1k2b: Difference between revisions

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[[Image:1k2b.jpg|left|200px]]<br /><applet load="1k2b" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1k2b.jpg|left|200px]]
caption="1k2b, resolution 1.7&Aring;" />
 
'''Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance'''<br />
{{Structure
|PDB= 1k2b |SIZE=350|CAPTION= <scene name='initialview01'>1k2b</scene>, resolution 1.7&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
|GENE=
}}
 
'''Combining Mutations in HIV-1 Protease to Understand Mechanisms of Resistance'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1K2B is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=NH2:'>NH2</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K2B OCA].  
1K2B is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K2B OCA].  


==Reference==
==Reference==
Combining mutations in HIV-1 protease to understand mechanisms of resistance., Mahalingam B, Boross P, Wang YF, Louis JM, Fischer CC, Tozser J, Harrison RW, Weber IT, Proteins. 2002 Jul 1;48(1):107-16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12012342 12012342]
Combining mutations in HIV-1 protease to understand mechanisms of resistance., Mahalingam B, Boross P, Wang YF, Louis JM, Fischer CC, Tozser J, Harrison RW, Weber IT, Proteins. 2002 Jul 1;48(1):107-16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12012342 12012342]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: NH2]]
[[Category: NH2]]
[[Category: dimer]]
[[Category: dimer]]
[[Category: double mutants]]
[[Category: double mutant]]
[[Category: hiv-1 protease]]
[[Category: hiv-1 protease]]
[[Category: inhibitor]]
[[Category: inhibitor]]
[[Category: x-ray diffraction]]
[[Category: x-ray diffraction]]


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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:11:37 2008''
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