4guq: Difference between revisions
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{{STRUCTURE_4guq| PDB=4guq | SCENE= }} | |||
===Structure of mutS139F p73 DNA binding domain complexed with 20BP DNA response element=== | |||
{{ABSTRACT_PUBMED_23892287}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref> | |||
==About this Structure== | |||
[[4guq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GUQ OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023892287</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Ethayathulla, A S.]] | |||
[[Category: Nguyen, H T.]] | |||
[[Category: Viadiu, H.]] | |||
[[Category: Beta-immunoglobulin]] | |||
[[Category: Transcription factor]] | |||
[[Category: Transcription-dna complex]] | |||
[[Category: Tumor suppressor]] | |||