1k90: Difference between revisions

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[[Image:1k90.gif|left|200px]]<br /><applet load="1k90" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1k90.gif|left|200px]]
caption="1k90, resolution 2.75&Aring;" />
 
'''Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP'''<br />
{{Structure
|PDB= 1k90 |SIZE=350|CAPTION= <scene name='initialview01'>1k90</scene>, resolution 2.75&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=YB:YTTERBIUM+(III)+ION'>YB</scene> and <scene name='pdbligand=3AT:3'-DEOXYADENOSINE-5'-TRIPHOSPHATE'>3AT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1]
|GENE=
}}
 
'''Crystal structure of the adenylyl cyclase domain of anthrax edema factor (EF) in complex with calmodulin and 3' deoxy-ATP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1K90 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=YB:'>YB</scene> and <scene name='pdbligand=3AT:'>3AT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1K90 with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb28_1.html Anthrax Toxin]]. Active as [http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K90 OCA].  
1K90 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 1K90 with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb28_1.html Anthrax Toxin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K90 OCA].  


==Reference==
==Reference==
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin., Drum CL, Yan SZ, Bard J, Shen YQ, Lu D, Soelaiman S, Grabarek Z, Bohm A, Tang WJ, Nature. 2002 Jan 24;415(6870):396-402. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11807546 11807546]
Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin., Drum CL, Yan SZ, Bard J, Shen YQ, Lu D, Soelaiman S, Grabarek Z, Bohm A, Tang WJ, Nature. 2002 Jan 24;415(6870):396-402. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11807546 11807546]
[[Category: Adenylate cyclase]]
[[Category: Adenylate cyclase]]
[[Category: Anthrax Toxin]]
[[Category: Anthrax Toxin]]
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[[Category: oedema factor adenylyl cyclase anthrax calmodulin]]
[[Category: oedema factor adenylyl cyclase anthrax calmodulin]]


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