1kc2: Difference between revisions

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[[Image:1kc2.jpg|left|200px]]<br /><applet load="1kc2" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1kc2.jpg|left|200px]]
caption="1kc2, resolution 2.10&Aring;" />
 
'''structure of the triple (Lys(beta)D3Ala, Asp(beta)C8Ala, AspCD2Ala) mutant of the Src SH2 domain bound to the PQpYEEIPI peptide'''<br />
{{Structure
|PDB= 1kc2 |SIZE=350|CAPTION= <scene name='initialview01'>1kc2</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CO:COBALT (II) ION'>CO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE=
}}
 
'''structure of the triple (Lys(beta)D3Ala, Asp(beta)C8Ala, AspCD2Ala) mutant of the Src SH2 domain bound to the PQpYEEIPI peptide'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1KC2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus] with <scene name='pdbligand=CO:'>CO</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KC2 OCA].  
1KC2 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KC2 OCA].  


==Reference==
==Reference==
Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface., Lubman OY, Waksman G, J Mol Biol. 2002 Feb 15;316(2):291-304. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11851339 11851339]
Dissection of the energetic coupling across the Src SH2 domain-tyrosyl phosphopeptide interface., Lubman OY, Waksman G, J Mol Biol. 2002 Feb 15;316(2):291-304. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11851339 11851339]
[[Category: Rous sarcoma virus]]
[[Category: Rous sarcoma virus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: sh2 domain]]
[[Category: sh2 domain]]


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