1kfl: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:1kfl.jpg|left|200px]]<br /><applet load="1kfl" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1kfl.jpg|left|200px]]
caption="1kfl, resolution 2.8&Aring;" />
 
'''Crystal structure of phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from E.coli complexed with Mn2+, PEP, and Phe'''<br />
{{Structure
|PDB= 1kfl |SIZE=350|CAPTION= <scene name='initialview01'>1kfl</scene>, resolution 2.8&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=PHE:PHENYLALANINE'>PHE</scene> and <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-deoxy-7-phosphoheptulonate_synthase 3-deoxy-7-phosphoheptulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.54 2.5.1.54]
|GENE= aroG ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Crystal structure of phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase (DAHP synthase) from E.coli complexed with Mn2+, PEP, and Phe'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
1KFL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=PHE:'>PHE</scene> and <scene name='pdbligand=PEP:'>PEP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/3-deoxy-7-phosphoheptulonate_synthase 3-deoxy-7-phosphoheptulonate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.54 2.5.1.54] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KFL OCA].  
1KFL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KFL OCA].  


==Reference==
==Reference==
Allosteric inhibition of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase alters the coordination of both substrates., Shumilin IA, Zhao C, Bauerle R, Kretsinger RH, J Mol Biol. 2002 Jul 26;320(5):1147-56. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12126632 12126632]
Allosteric inhibition of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase alters the coordination of both substrates., Shumilin IA, Zhao C, Bauerle R, Kretsinger RH, J Mol Biol. 2002 Jul 26;320(5):1147-56. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12126632 12126632]
[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
[[Category: 3-deoxy-7-phosphoheptulonate synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
Line 27: Line 36:
[[Category: feedback regulation]]
[[Category: feedback regulation]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:33:37 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:16:48 2008''
Retrieved from "https://proteopedia.org/1kfl"