3zxo: Difference between revisions
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{{STRUCTURE_3zxo| PDB=3zxo | SCENE= }} | {{STRUCTURE_3zxo| PDB=3zxo | SCENE= }} | ||
===CRYSTAL STRUCTURE OF THE MUTANT ATP-BINDING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS=== | ===CRYSTAL STRUCTURE OF THE MUTANT ATP-BINDING DOMAIN OF MYCOBACTERIUM TUBERCULOSIS DOSS=== | ||
{{ABSTRACT_PUBMED_23486471}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DEVS_MYCTU DEVS_MYCTU]] Member of the two-component regulatory system DevR/DevS (DosR/DosS) involved in onset of the dormancy response. May act as a redox sensor (rather than a direct hypoxia sensor); the normal (aerobic growth) state is the Fe(3+) form, while the reduced (anaerobic growth) Fe(2+) form is probably active for phosphate transfer. It is probably reduced by flavin nucleotides such as FMN and FAD. May be the primary sensor for CO. Donates a phosphate group to DevR (DosR).<ref>PMID:15033981</ref><ref>PMID:18474359</ref><ref>PMID:18400743</ref> | |||
==About this Structure== | ==About this Structure== | ||
[[3zxo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[3zxo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_h37rv Mycobacterium tuberculosis h37rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZXO OCA]. | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:016213520</ref><references group="xtra"/> | <ref group="xtra">PMID:016213520</ref><references group="xtra"/><references/> | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis h37rv]] | ||
[[Category: Cho, H J.]] | [[Category: Cho, H J.]] | ||
[[Category: Cho, H Y.]] | [[Category: Cho, H Y.]] | ||
[[Category: Kang, B S.]] | [[Category: Kang, B S.]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
