Introduction to Evolutionary Conservation: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) |
Eric Martz (talk | contribs) |
||
| Line 74: | Line 74: | ||
===Locations of Mutations in 3D Model=== | ===Locations of Mutations in 3D Model=== | ||
<Structure load='' size='350' frame='true' align='right' caption='MeCp2 protein bound to DNA (crystal structure [[ | <Structure load='' size='350' frame='true' align='right' caption='MeCp2 protein bound to DNA (crystal structure [[3c2i]]). Conservation calculated by [[ConSurfDB_vs._ConSurf|ConSurf-DB]].' scene='Introduction_to_Evolutionary_Conservation/Conservation/1' /> | ||
The positions of <font color='#c000a8'>'''conserved Arg133'''</font> and <font color='00a0a0'>'''variable Glu143'''</font> are highlighted with <span style="background:black; color:yellow;">''' yellow '''</span> halos. You can see that <font color='#c000a8'>'''conserved Arg133'''</font> is in intimate contact with the <font color='#d46a42'>'''DNA'''</font>, while <font color='00a0a0'>'''variable Glu143'''</font> is on the surface, and remote from the contact with the <font color='#d46a42'>'''DNA'''</font>. | The positions of <font color='#c000a8'>'''conserved Arg133'''</font> and <font color='00a0a0'>'''variable Glu143'''</font> are highlighted with <span style="background:black; color:yellow;">''' yellow '''</span> halos. You can see that <font color='#c000a8'>'''conserved Arg133'''</font> is in intimate contact with the <font color='#d46a42'>'''DNA'''</font>, while <font color='00a0a0'>'''variable Glu143'''</font> is on the surface, and remote from the contact with the <font color='#d46a42'>'''DNA'''</font>. | ||
