4fl9: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4fl9|  PDB=4fl9  |  SCENE=  }}
===Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution===


The entry 4fl9 is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/HSP7C_BOVIN HSP7C_BOVIN]] Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (By similarity).


Authors: Grimm, C.
==About this Structure==
 
[[4fl9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FL9 OCA].
Description: Crystal Structure of bovine hsc70(aa1-554)E213A/D214A at 1.9A Resolution
[[Category: Bos taurus]]
[[Category: Grimm, C.]]
[[Category: Heat shock protein]]
[[Category: Transcription]]