1kli: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 1: Line 1:
[[Image:1kli.jpg|left|200px]]<br /><applet load="1kli" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1kli.jpg|left|200px]]
caption="1kli, resolution 1.69&Aring;" />
 
'''Cofactor-and substrate-assisted activation of factor VIIa'''<br />
{{Structure
|PDB= 1kli |SIZE=350|CAPTION= <scene name='initialview01'>1kli</scene>, resolution 1.69&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Coagulation_factor_VIIa Coagulation factor VIIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.21 3.4.21.21]
|GENE=
}}
 
'''Cofactor-and substrate-assisted activation of factor VIIa'''
 


==Overview==
==Overview==
Line 10: Line 19:


==About this Structure==
==About this Structure==
1KLI is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=BEN:'>BEN</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Coagulation_factor_VIIa Coagulation factor VIIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.21 3.4.21.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KLI OCA].  
1KLI is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KLI OCA].  


==Reference==
==Reference==
Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions., Sichler K, Banner DW, D'Arcy A, Hopfner KP, Huber R, Bode W, Kresse GB, Kopetzki E, Brandstetter H, J Mol Biol. 2002 Sep 20;322(3):591-603. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12225752 12225752]
Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions., Sichler K, Banner DW, D'Arcy A, Hopfner KP, Huber R, Bode W, Kresse GB, Kopetzki E, Brandstetter H, J Mol Biol. 2002 Sep 20;322(3):591-603. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12225752 12225752]
[[Category: Coagulation factor VIIa]]
[[Category: Coagulation factor VIIa]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
Line 35: Line 44:
[[Category: substrate-assisted catalysis]]
[[Category: substrate-assisted catalysis]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:35:24 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:19:00 2008''
Retrieved from "https://proteopedia.org/1kli"