4bd9: Difference between revisions

Revision as of 04:56, 18 July 2013

[CBPA4_HUMAN] Metalloprotease that could be involved in the histone hyperacetylation pathway.^[1]

4bd9 is a 2 chain structure with sequence from Homo sapiens and Sabellastarte magnifica. Full crystallographic information is available from OCA.

Alonso Del Rivero M, Reytor ML, Trejo SA, Chavez MA, Aviles FX, Reverter D. A Noncanonical Mechanism of Carboxypeptidase Inhibition Revealed by the Crystal Structure of the Tri-Kunitz SmCI in Complex with Human CPA4. Structure. 2013 Jul 2;21(7):1118-26. doi: 10.1016/j.str.2013.04.021. Epub 2013, Jun 6. PMID:23746805 doi:10.1016/j.str.2013.04.021

↑ Huang H, Reed CP, Zhang JS, Shridhar V, Wang L, Smith DI. Carboxypeptidase A3 (CPA3): a novel gene highly induced by histone deacetylase inhibitors during differentiation of prostate epithelial cancer cells. Cancer Res. 1999 Jun 15;59(12):2981-8. PMID:10383164

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-'''Unreleased structure'''
+{{STRUCTURE_4bd9|  PDB=4bd9  |  SCENE=  }}
+===Structure of the complex between SmCI and human carboxypeptidase A4===
+{{ABSTRACT_PUBMED_23746805}}
-The entry 4bd9 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/CBPA4_HUMAN CBPA4_HUMAN]] Metalloprotease that could be involved in the histone hyperacetylation pathway.<ref>PMID:10383164</ref>
-Authors: Alonso-del-Ribero, M., Reytor, M.L., Trejo, S., Chavez, M.A., Aviles, F.X., Reverter, D.
+==About this Structure==
+[[4bd9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Sabellastarte_magnifica Sabellastarte magnifica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BD9 OCA].
-Description: Structure of the complex between SmCI and human carboxypeptidase A4
+==Reference==
+<ref group="xtra">PMID:023746805</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Sabellastarte magnifica]]
+[[Category: Alonso-del-Ribero, M.]]
+[[Category: Aviles, F X.]]
+[[Category: Chavez, M A.]]
+[[Category: Reverter, D.]]
+[[Category: Reytor, M L.]]
+[[Category: Trejo, S A.]]
+[[Category: Hydrolase-hydrolase inhibitor complex]]
+[[Category: Serine protease inhibitor]]