1ktz: Difference between revisions

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[[Image:1ktz.gif|left|200px]]<br /><applet load="1ktz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ktz.gif|left|200px]]
caption="1ktz, resolution 2.15&Aring;" />
 
'''Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3'''<br />
{{Structure
|PDB= 1ktz |SIZE=350|CAPTION= <scene name='initialview01'>1ktz</scene>, resolution 2.15&Aring;
|SITE=
|LIGAND=
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE=
}}
 
'''Crystal Structure of the Human TGF-beta Type II Receptor Extracellular Domain in Complex with TGF-beta3'''
 


==Overview==
==Overview==
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==Disease==
==Disease==
Known diseases associated with this structure: Aortic aneurysm, familial thoracic 3 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Arrhythmogenic right ventricular dysplasia 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190230 190230]], Colon cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Esophageal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Loeys-Dietz syndrome OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Marfan syndrome, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]]
Known diseases associated with this structure: Arrhythmogenic right ventricular dysplasia 1 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190230 190230]], Colorectal cancer, hereditary nonpolyposis, type 6 OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Esophageal cancer OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Loeys-Dietz syndrome, type 1B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]], Loeys-Dietz syndrome, type 2B OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=190182 190182]]


==About this Structure==
==About this Structure==
1KTZ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KTZ OCA].  
1KTZ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KTZ OCA].  


==Reference==
==Reference==
Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex., Hart PJ, Deep S, Taylor AB, Shu Z, Hinck CS, Hinck AP, Nat Struct Biol. 2002 Mar;9(3):203-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=11850637 11850637]
Crystal structure of the human TbetaR2 ectodomain--TGF-beta3 complex., Hart PJ, Deep S, Taylor AB, Shu Z, Hinck CS, Hinck AP, Nat Struct Biol. 2002 Mar;9(3):203-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11850637 11850637]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: cytokine-receptor complex]]
[[Category: cytokine-receptor complex]]


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