1kwr: Difference between revisions

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[[Image:1kwr.jpg|left|200px]]<br /><applet load="1kwr" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1kwr.jpg|left|200px]]
caption="1kwr, resolution 2.25&Aring;" />
 
'''HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH INHIBITOR 0134-36'''<br />
{{Structure
|PDB= 1kwr |SIZE=350|CAPTION= <scene name='initialview01'>1kwr</scene>, resolution 2.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=SG2:1-METHYL-3-OXO-1,3-DIHYDRO-BENZO[C]ISOTHIAZOLE-5-SULFONIC ACID AMIDE'>SG2</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
|GENE=
}}
 
'''HUMAN CARBONIC ANHYDRASE II COMPLEXED WITH INHIBITOR 0134-36'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1KWR is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=SG2:'>SG2</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KWR OCA].  
1KWR is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KWR OCA].  


==Reference==
==Reference==
Successful virtual screening for novel inhibitors of human carbonic anhydrase: strategy and experimental confirmation., Gruneberg S, Stubbs MT, Klebe G, J Med Chem. 2002 Aug 15;45(17):3588-602. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12166932 12166932]
Successful virtual screening for novel inhibitors of human carbonic anhydrase: strategy and experimental confirmation., Gruneberg S, Stubbs MT, Klebe G, J Med Chem. 2002 Aug 15;45(17):3588-602. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12166932 12166932]
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: zinc]]
[[Category: zinc]]


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