Sandbox 50: Difference between revisions

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==Solvent==

The <scene name='Sandbox_50/Ak_water6/1'>solvent</scene>, which is water (blue), can be co-crystallized with the enzyme. The water can be found all around the protein but there is also some water molecules in the active site, around the ligand. This further indicates why the hydrophilic residues are found on the surface, and the nonpolar residues are buried away. The water creates a hydrophilic environment, and ~~drives~~ the hydrophobic ~~effect~~, ~~burying~~ the hydrophobic ~~residues in~~ the ~~interior~~. The hydrophilic residues in the active site cause water to be present there, and also make it easier for the ligand to enter. For the most part, there are not water molecules in between the secondary structure because that is where the hydrophobic residues reside, but there are some water molecules in the open spaces of the backbone.

The <scene name='Sandbox_50/Ak_water6/1'>solvent</scene>, which is water (blue), can be co-crystallized with the enzyme. The water can be found all around the protein but there is also some water molecules in the active site, around the ligand. This further indicates why the hydrophilic residues are found on the surface, and the nonpolar residues are buried away. The water creates a hydrophilic environment, and the hydrophobic residues aggregate together in the interior, and the hydrophobic effect drives the water out. The hydrophilic residues in the active site cause water to be present there, and also make it easier for the ligand to enter. For the most part, there are not water molecules in between the secondary structure because that is where the hydrophobic residues reside, but there are some water molecules in the open spaces of the backbone.

Sandbox 50: Difference between revisions

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Revision as of 23:29, 18 October 2012 view source Student (talk \| contribs) students 33,923 edits No edit summary ← Older edit		Revision as of 01:34, 19 October 2012 view source Student (talk \| contribs) students 33,923 edits No edit summary Newer edit →
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	==Solvent==		==Solvent==

	The <scene name='Sandbox_50/Ak_water6/1'>solvent</scene>, which is water (blue), can be co-crystallized with the enzyme. The water can be found all around the protein but there is also some water molecules in the active site, around the ligand. This further indicates why the hydrophilic residues are found on the surface, and the nonpolar residues are buried away. The water creates a hydrophilic environment, and ~~drives~~ the hydrophobic ~~effect~~, ~~burying~~ the hydrophobic ~~residues in~~ the ~~interior~~. The hydrophilic residues in the active site cause water to be present there, and also make it easier for the ligand to enter. For the most part, there are not water molecules in between the secondary structure because that is where the hydrophobic residues reside, but there are some water molecules in the open spaces of the backbone.		The <scene name='Sandbox_50/Ak_water6/1'>solvent</scene>, which is water (blue), can be co-crystallized with the enzyme. The water can be found all around the protein but there is also some water molecules in the active site, around the ligand. This further indicates why the hydrophilic residues are found on the surface, and the nonpolar residues are buried away. The water creates a hydrophilic environment, and the hydrophobic residues aggregate together in the interior, and the hydrophobic effect drives the water out. The hydrophilic residues in the active site cause water to be present there, and also make it easier for the ligand to enter. For the most part, there are not water molecules in between the secondary structure because that is where the hydrophobic residues reside, but there are some water molecules in the open spaces of the backbone.