1kzp: Difference between revisions

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[[Image:1kzp.jpg|left|200px]]<br /><applet load="1kzp" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1kzp.jpg|left|200px]]
caption="1kzp, resolution 2.10&Aring;" />
 
'''PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYLATED K-RAS4B PEPTIDE PRODUCT'''<br />
{{Structure
|PDB= 1kzp |SIZE=350|CAPTION= <scene name='initialview01'>1kzp</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=FAR:FARNESYL'>FAR</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21]
|GENE=
}}
 
'''PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH A FARNESYLATED K-RAS4B PEPTIDE PRODUCT'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1KZP is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=FAR:'>FAR</scene> and <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Squalene_synthase Squalene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.21 2.5.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZP OCA].  
1KZP is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZP OCA].  


==Reference==
==Reference==
Reaction path of protein farnesyltransferase at atomic resolution., Long SB, Casey PJ, Beese LS, Nature. 2002 Oct 10;419(6907):645-50. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12374986 12374986]
Reaction path of protein farnesyltransferase at atomic resolution., Long SB, Casey PJ, Beese LS, Nature. 2002 Oct 10;419(6907):645-50. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12374986 12374986]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: ras cancer]]
[[Category: ras cancer]]


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