1w50: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_1w50| PDB=1w50 | SCENE= }} | {{STRUCTURE_1w50| PDB=1w50 | SCENE= }} | ||
===APO STRUCTURE OF BACE (BETA SECRETASE)=== | ===APO STRUCTURE OF BACE (BETA SECRETASE)=== | ||
{{ABSTRACT_PUBMED_15451669}} | {{ABSTRACT_PUBMED_15451669}} | ||
Revision as of 09:48, 11 March 2013
| |||||||||||||
| 1w50, resolution 1.75Å (default scene) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ligands: | IOD | ||||||||||||
| Activity: | Memapsin 2, with EC number 3.4.23.46 | ||||||||||||
| Related: | 1fkn, 1m4h, 1py1, 1sgz, 1ujj, 1ujk, 1w51 | ||||||||||||
| |||||||||||||
| |||||||||||||
| Resources: | FirstGlance, OCA, RCSB, PDBsum | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
APO STRUCTURE OF BACE (BETA SECRETASE)
Template:ABSTRACT PUBMED 15451669
About this Structure
1w50 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Patel S, Vuillard L, Cleasby A, Murray CW, Yon J. Apo and inhibitor complex structures of BACE (beta-secretase). J Mol Biol. 2004 Oct 15;343(2):407-16. PMID:15451669 doi:10.1016/j.jmb.2004.08.018
- Xu Y, Li MJ, Greenblatt H, Chen W, Paz A, Dym O, Peleg Y, Chen T, Shen X, He J, Jiang H, Silman I, Sussman JL. Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations. Acta Crystallogr D Biol Crystallogr. 2012 Jan;68(Pt 1):13-25. Epub 2011 Dec 9. PMID:22194329 doi:10.1107/S0907444911047251
