1cm4: Difference between revisions
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{{STRUCTURE_1cm4| PDB=1cm4 | SCENE= }} | {{STRUCTURE_1cm4| PDB=1cm4 | SCENE= }} | ||
===Motions of calmodulin-four-conformer refinement=== | |||
{{ABSTRACT_PUBMED_9438860}} | |||
=== | ==Function== | ||
[[http://www.uniprot.org/uniprot/KCC2A_RAT KCC2A_RAT]] CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.<ref>PMID:15312654</ref> | |||
==About this Structure== | ==About this Structure== | ||
| Line 14: | Line 13: | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:009438860</ref><references group="xtra"/> | <ref group="xtra">PMID:009438860</ref><references group="xtra"/><references/> | ||
[[Category: Bos taurus]] | [[Category: Bos taurus]] | ||
[[Category: Calcium/calmodulin-dependent protein kinase]] | [[Category: Calcium/calmodulin-dependent protein kinase]] | ||
[[Category: Phillips, G N.]] | [[Category: Phillips, G N.]] | ||
[[Category: Wall, M E.]] | [[Category: Wall, M E.]] | ||
[[Category: Calcium-binding-transferase complex]] | |||
[[Category: Ef-hand calcium-binding protein]] | [[Category: Ef-hand calcium-binding protein]] | ||
Revision as of 11:19, 24 July 2013
Motions of calmodulin-four-conformer refinement
Template:ABSTRACT PUBMED 9438860
Function
[KCC2A_RAT] CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity.[1]
About this Structure
1cm4 is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
See Also
Reference
- Wall ME, Clarage JB, Phillips GN. Motions of calmodulin characterized using both Bragg and diffuse X-ray scattering. Structure. 1997 Dec 15;5(12):1599-612. PMID:9438860
- ↑ Krapivinsky G, Medina I, Krapivinsky L, Gapon S, Clapham DE. SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation. Neuron. 2004 Aug 19;43(4):563-74. PMID:15312654 doi:10.1016/j.neuron.2004.08.003
