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[[Image:3op3.png|left|200px]]
==Crystal Structure of Cell Division Cycle 25C Protein Isoform A from Homo sapiens==
 
<StructureSection load='3op3' size='340' side='right' caption='[[3op3]], [[Resolution|resolution]] 2.63&Aring;' scene=''>
{{STRUCTURE_3op3|  PDB=3op3  |  SCENE=  }}
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3op3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OP3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3OP3 FirstGlance]. <br>
===Crystal Structure of Cell Division Cycle 25C Protein Isoform A from Homo sapiens===
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CDC25C ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
 
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3op3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3op3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3op3 RCSB], [http://www.ebi.ac.uk/pdbsum/3op3 PDBsum]</span></td></tr>
[[3op3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OP3 OCA].  
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/3op3_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
*[[Tyrosine phosphatase|Tyrosine phosphatase]]
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Protein-tyrosine-phosphatase]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith, C H]]
[[Category: Ball, L.]]
[[Category: Ball, L]]
[[Category: Barr, A.]]
[[Category: Barr, A]]
[[Category: Bountra, C.]]
[[Category: Bountra, C]]
[[Category: Delft, F von.]]
[[Category: Delft, F von]]
[[Category: Edwards, A.]]
[[Category: Edwards, A]]
[[Category: Gileadi, O.]]
[[Category: Gileadi, O]]
[[Category: Hatzos, C.]]
[[Category: Hatzos, C]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Johansson, C.]]
[[Category: Johansson, C]]
[[Category: Kim, Y.]]
[[Category: Kim, Y]]
[[Category: Knapp, S.]]
[[Category: Knapp, S]]
[[Category: Muniz, J.]]
[[Category: Muniz, J]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Structural genomic]]
[[Category: Savitsky, P.]]
[[Category: Savitsky, P]]
[[Category: Vollmar, M.]]
[[Category: Vollmar, M]]
[[Category: Weger, A.]]
[[Category: Weger, A]]
[[Category: Weigelt, J.]]
[[Category: Weigelt, J]]
[[Category: Alpha-beta-alpha sandwich]]
[[Category: Alpha-beta-alpha sandwich]]
[[Category: Cytosol]]
[[Category: Cytosol]]
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[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Sgc]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]

Revision as of 11:50, 9 December 2014

Crystal Structure of Cell Division Cycle 25C Protein Isoform A from Homo sapiens

3op3, resolution 2.63Å

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