1lco: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:1lco.jpg|left|200px]]<br /><applet load="1lco" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1lco.jpg|left|200px]]
caption="1lco, resolution 2.9&Aring;" />
 
'''X-RAY STRUCTURE OF TWO COMPLEXES OF THE Y143F FLAVOCYTOCHROME B2 MUTANT CRYSTALLIZED IN THE PRESENCE OF LACTATE OR PHENYL-LACTATE'''<br />
{{Structure
|PDB= 1lco |SIZE=350|CAPTION= <scene name='initialview01'>1lco</scene>, resolution 2.9&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene> and <scene name='pdbligand=PPY:3-PHENYLPYRUVIC ACID'>PPY</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase_(cytochrome) L-lactate dehydrogenase (cytochrome)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.2.3 1.1.2.3]
|GENE= PGR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
}}
 
'''X-RAY STRUCTURE OF TWO COMPLEXES OF THE Y143F FLAVOCYTOCHROME B2 MUTANT CRYSTALLIZED IN THE PRESENCE OF LACTATE OR PHENYL-LACTATE'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
1LCO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=HEM:'>HEM</scene>, <scene name='pdbligand=FMN:'>FMN</scene> and <scene name='pdbligand=PPY:'>PPY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/L-lactate_dehydrogenase_(cytochrome) L-lactate dehydrogenase (cytochrome)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.2.3 1.1.2.3] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LCO OCA].  
1LCO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LCO OCA].  


==Reference==
==Reference==
X-ray structure of two complexes of the Y143F flavocytochrome b2 mutant crystallized in the presence of lactate or phenyl lactate., Tegoni M, Begotti S, Cambillau C, Biochemistry. 1995 Aug 8;34(31):9840-50. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7632684 7632684]
X-ray structure of two complexes of the Y143F flavocytochrome b2 mutant crystallized in the presence of lactate or phenyl lactate., Tegoni M, Begotti S, Cambillau C, Biochemistry. 1995 Aug 8;34(31):9840-50. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7632684 7632684]
[[Category: L-lactate dehydrogenase (cytochrome)]]
[[Category: L-lactate dehydrogenase (cytochrome)]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
Line 21: Line 30:
[[Category: electron transport]]
[[Category: electron transport]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 13:43:47 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:29:27 2008''