2ydx: Difference between revisions
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{{STRUCTURE_2ydx| PDB=2ydx | SCENE= }} | {{STRUCTURE_2ydx| PDB=2ydx | SCENE= }} | ||
===Crystal structure of human S-adenosylmethionine synthetase 2, beta subunit=== | |||
{{ABSTRACT_PUBMED_23425511}} | |||
=== | ==Function== | ||
[[http://www.uniprot.org/uniprot/MAT2B_HUMAN MAT2B_HUMAN]] Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition.<ref>PMID:10644686</ref> | |||
==About this Structure== | ==About this Structure== | ||
| Line 10: | Line 10: | ||
==See Also== | ==See Also== | ||
*[[ | *[[SAM synthetase|SAM synthetase]] | ||
==Reference== | |||
<ref group="xtra">PMID:023425511</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
[[Category: Bountra, C.]] | [[Category: Bountra, C.]] | ||
[[Category: Delft, F | [[Category: Delft, F von.]] | ||
[[Category: Edwards, A M.]] | [[Category: Edwards, A M.]] | ||
[[Category: Gileadi, O.]] | [[Category: Gileadi, O.]] | ||
Revision as of 11:35, 24 July 2013
Crystal structure of human S-adenosylmethionine synthetase 2, beta subunit
Template:ABSTRACT PUBMED 23425511
Function
[MAT2B_HUMAN] Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition.[1]
About this Structure
2ydx is a 5 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Shafqat N, Muniz JR, Pilka ES, Papagrigoriou E, von Delft F, Oppermann U, Yue WW. Insight into S-adenosylmethionine biosynthesis from the crystal structures of the human methionine adenosyltransferase catalytic and regulatory subunits. Biochem J. 2013 May 15;452(1):27-36. doi: 10.1042/BJ20121580. PMID:23425511 doi:10.1042/BJ20121580