1lri: Difference between revisions
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
[[Image:1lri.gif|left|200px]] | [[Image:1lri.gif|left|200px]] | ||
'''BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX''' | {{Structure | ||
|PDB= 1lri |SIZE=350|CAPTION= <scene name='initialview01'>1lri</scene>, resolution 1.45Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX''' | |||
==Overview== | ==Overview== | ||
| Line 7: | Line 16: | ||
==About this Structure== | ==About this Structure== | ||
1LRI is a [ | 1LRI is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Phytophthora_cryptogea Phytophthora cryptogea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LRI OCA]. | ||
==Reference== | ==Reference== | ||
The 1.45 A resolution structure of the cryptogein-cholesterol complex: a close-up view of a sterol carrier protein (SCP) active site., Lascombe MB, Ponchet M, Venard P, Milat ML, Blein JP, Prange T, Acta Crystallogr D Biol Crystallogr. 2002 Sep;58(Pt 9):1442-7. Epub 2002, Aug 23. PMID:[http:// | The 1.45 A resolution structure of the cryptogein-cholesterol complex: a close-up view of a sterol carrier protein (SCP) active site., Lascombe MB, Ponchet M, Venard P, Milat ML, Blein JP, Prange T, Acta Crystallogr D Biol Crystallogr. 2002 Sep;58(Pt 9):1442-7. Epub 2002, Aug 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12198300 12198300] | ||
[[Category: Phytophthora cryptogea]] | [[Category: Phytophthora cryptogea]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| Line 25: | Line 34: | ||
[[Category: sterol carrier protein]] | [[Category: sterol carrier protein]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 12:34:16 2008'' | ||
Revision as of 10:34, 20 March 2008
| |||||||||||||
| 1lri, resolution 1.45Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Ligands: | CL and CLR | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
BETA-CRYPTOGEIN-CHOLESTEROL COMPLEX
Overview
Cryptogein is a small 10 kDa elicitor produced by the phytoparasitic oomycete Phytophthora cryptogea. The protein also displays a sterol carrier activity. The native protein crystallizes in space group P4(1)22, with unit-cell parameters a = b = 46.51, c = 134.9 A (diffraction limit: 2.1 A). Its complex with cholesterol crystallizes in space group C222(1), with unit-cell parameters a = 30.96, b = 94.8, c = 65.3 A and a resolution enhanced to 1.45 A. The large inner non-specific hydrophobic cavity is able to accommodate a large variety of 3-beta-hydroxy sterols. Cryptogein probably acts as a sterol shuttle helping the pathogen to grow and complete its life cycle.
About this Structure
1LRI is a Single protein structure of sequence from Phytophthora cryptogea. Full crystallographic information is available from OCA.
Reference
The 1.45 A resolution structure of the cryptogein-cholesterol complex: a close-up view of a sterol carrier protein (SCP) active site., Lascombe MB, Ponchet M, Venard P, Milat ML, Blein JP, Prange T, Acta Crystallogr D Biol Crystallogr. 2002 Sep;58(Pt 9):1442-7. Epub 2002, Aug 23. PMID:12198300
Page seeded by OCA on Thu Mar 20 12:34:16 2008
