2x4r: Difference between revisions
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{{STRUCTURE_2x4r| PDB=2x4r | SCENE= }} | {{STRUCTURE_2x4r| PDB=2x4r | SCENE= }} | ||
===CRYSTAL STRUCTURE OF MHC CLASS I HLA-A2.1 BOUND TO CYTOMEGALOVIRUS (CMV) PP65 EPITOPE=== | ===CRYSTAL STRUCTURE OF MHC CLASS I HLA-A2.1 BOUND TO CYTOMEGALOVIRUS (CMV) PP65 EPITOPE=== | ||
{{ABSTRACT_PUBMED_19655750}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/1A02_HUMAN 1A02_HUMAN]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/PP65_HCMVA PP65_HCMVA]] Counteracts the host antiviral immune response when activated and phosphorylated, by preventing IRF3 from entering the nucleus. Also participates in the transactivation of viral major immediate-early genes by the recruitment of host IFI16 to the promoters pf these genes.<ref>PMID:15452220</ref><ref>PMID:20504932</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
<ref group="xtra">PMID:019655750</ref><references group="xtra"/> | <ref group="xtra">PMID:019655750</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Celie, P H.N.]] | [[Category: Celie, P H.N.]] | ||
