3dpy: Difference between revisions

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~~[[Image:3dpy.png|left|200px]]~~

===Protein farnesyltransferase complexed with FPP and caged TKCVIM substrate===

==Function==

[[http://www.uniprot.org/uniprot/FNTA_RAT FNTA_RAT]] Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity). [[http://www.uniprot.org/uniprot/FNTB_RAT FNTB_RAT]] Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.

==About this Structure==

[[3dpy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DPY OCA].

==~~See Also~~==

==Reference==

*[[Farnesyltransferase|Farnesyltransferase]]

[[Category: Protein farnesyltransferase]]

[[Category: Rattus norvegicus]]

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-[[Image:3dpy.png|left|200px]]
 {{STRUCTURE_3dpy|  PDB=3dpy  |  SCENE=  }}
 ===Protein farnesyltransferase complexed with FPP and caged TKCVIM substrate===
+{{ABSTRACT_PUBMED_18844669}}
+==Function==
+[[http://www.uniprot.org/uniprot/FNTA_RAT FNTA_RAT]] Catalyzes the transfer of a farnesyl or geranyl-geranyl moiety from farnesyl or geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. The alpha subunit is thought to participate in a stable complex with the substrate. The beta subunit binds the peptide substrate. Through RAC1 prenylation and activation may positively regulate neuromuscular junction development downstream of MUSK (By similarity). [[http://www.uniprot.org/uniprot/FNTB_RAT FNTB_RAT]] Catalyzes the transfer of a farnesyl moiety from farnesyl pyrophosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
 ==About this Structure==
 [[3dpy]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DPY OCA].
-==See Also==
+==Reference==
-*[[Farnesyltransferase|Farnesyltransferase]]
+<ref group="xtra">PMID:018844669</ref><references group="xtra"/><references/>
 [[Category: Protein farnesyltransferase]]
 [[Category: Rattus norvegicus]]