2dnc: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_2dnc| PDB=2dnc | SCENE= }} | {{STRUCTURE_2dnc| PDB=2dnc | SCENE= }} | ||
===Solution Structure of RSGI RUH-054, a lipoyl domain from human 2-oxoacid dehydrogenase=== | |||
=== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/ODPX_HUMAN ODPX_HUMAN]] Defects in PDHX are the cause of pyruvate dehydrogenase E3-binding protein deficiency (PDHXD) [MIM:[http://omim.org/entry/245349 245349]].<ref>PMID:9399911</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/ODPX_HUMAN ODPX_HUMAN]] Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. | |||
==About this Structure== | ==About this Structure== | ||
| Line 11: | Line 13: | ||
==See Also== | ==See Also== | ||
*[[Pyruvate dehydrogenase|Pyruvate dehydrogenase]] | *[[Pyruvate dehydrogenase|Pyruvate dehydrogenase]] | ||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hayashi, F.]] | [[Category: Hayashi, F.]] | ||
