1lzv: Difference between revisions

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[[Image:1lzv.jpg|left|200px]]<br /><applet load="1lzv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1lzv.jpg|left|200px]]
caption="1lzv, resolution 2.30&Aring;" />
 
'''Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II'''<br />
{{Structure
|PDB= 1lzv |SIZE=350|CAPTION= <scene name='initialview01'>1lzv</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC ION'>ZN</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1]
|GENE=
}}
 
'''Site-Specific Mutant (Tyr7 replaced with His) of Human Carbonic Anhydrase II'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1LZV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ZN:'>ZN</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Carbonate_dehydratase Carbonate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.1 4.2.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LZV OCA].  
1LZV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LZV OCA].  


==Reference==
==Reference==
Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase., Tu C, Qian M, An H, Wadhwa NR, Duda D, Yoshioka C, Pathak Y, McKenna R, Laipis PJ, Silverman DN, J Biol Chem. 2002 Oct 11;277(41):38870-6. Epub 2002 Aug 8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12171926 12171926]
Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase., Tu C, Qian M, An H, Wadhwa NR, Duda D, Yoshioka C, Pathak Y, McKenna R, Laipis PJ, Silverman DN, J Biol Chem. 2002 Oct 11;277(41):38870-6. Epub 2002 Aug 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12171926 12171926]
[[Category: Carbonate dehydratase]]
[[Category: Carbonate dehydratase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: zinc metalloenzyme]]
[[Category: zinc metalloenzyme]]


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