1m13: Difference between revisions

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[[Image:1m13.gif|left|200px]]<br /><applet load="1m13" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1m13.gif|left|200px]]
caption="1m13, resolution 2.15&Aring;" />
 
'''Crystal Structure of the Human Pregane X Receptor Ligand Binding Domain in Complex with Hyperforin, a Constituent of St. John's Wort'''<br />
{{Structure
|PDB= 1m13 |SIZE=350|CAPTION= <scene name='initialview01'>1m13</scene>, resolution 2.15&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=HYF:4-HYDROXY-5-ISOBUTYRYL-6-METHYL-1,3,7-TRIS-(3-METHYL-BUT-2-ENYL)-6-(4-METHYL-PENT-3-ENYL)-BICYCLO[3.3.1]NON-3-ENE-2,9-DIONE'>HYF</scene>
|ACTIVITY=
|GENE= NR1I2 or PXR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal Structure of the Human Pregane X Receptor Ligand Binding Domain in Complex with Hyperforin, a Constituent of St. John's Wort'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1M13 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=HYF:'>HYF</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M13 OCA].  
1M13 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M13 OCA].  


==Reference==
==Reference==
2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin., Watkins RE, Maglich JM, Moore LB, Wisely GB, Noble SM, Davis-Searles PR, Lambert MH, Kliewer SA, Redinbo MR, Biochemistry. 2003 Feb 18;42(6):1430-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12578355 12578355]
2.1 A crystal structure of human PXR in complex with the St. John's wort compound hyperforin., Watkins RE, Maglich JM, Moore LB, Wisely GB, Noble SM, Davis-Searles PR, Lambert MH, Kliewer SA, Redinbo MR, Biochemistry. 2003 Feb 18;42(6):1430-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12578355 12578355]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: protein-ligand complex]]
[[Category: protein-ligand complex]]


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Retrieved from "https://proteopedia.org/1m13"