1m52: Difference between revisions

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[[Image:1m52.gif|left|200px]]<br /><applet load="1m52" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1m52.gif|left|200px]]
caption="1m52, resolution 2.60&Aring;" />
 
'''Crystal Structure of the c-Abl Kinase domain in complex with PD173955'''<br />
{{Structure
|PDB= 1m52 |SIZE=350|CAPTION= <scene name='initialview01'>1m52</scene>, resolution 2.60&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene> and <scene name='pdbligand=P17:6-(2,6-DICHLORO-PHENYL)-8-METHYL-2-(3-METHYLSULFANYL-PHENYLAMINO)-8H-PYRIDO[2,3-D]PYRIMIDIN-7-ONE'>P17</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
|GENE=
}}
 
'''Crystal Structure of the c-Abl Kinase domain in complex with PD173955'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1M52 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=MES:'>MES</scene> and <scene name='pdbligand=P17:'>P17</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M52 OCA].  
1M52 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1M52 OCA].  


==Reference==
==Reference==
Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)., Nagar B, Bornmann WG, Pellicena P, Schindler T, Veach DR, Miller WT, Clarkson B, Kuriyan J, Cancer Res. 2002 Aug 1;62(15):4236-43. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12154025 12154025]
Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571)., Nagar B, Bornmann WG, Pellicena P, Schindler T, Veach DR, Miller WT, Clarkson B, Kuriyan J, Cancer Res. 2002 Aug 1;62(15):4236-43. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12154025 12154025]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: pd173955]]
[[Category: pd173955]]


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