1yb1: Difference between revisions
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{{STRUCTURE_1yb1| PDB=1yb1 | SCENE= }} | {{STRUCTURE_1yb1| PDB=1yb1 | SCENE= }} | ||
===Crystal structure of human 17-beta-hydroxysteroid dehydrogenase type XI=== | ===Crystal structure of human 17-beta-hydroxysteroid dehydrogenase type XI=== | ||
==Function== | |||
[[http://www.uniprot.org/uniprot/DHB11_HUMAN DHB11_HUMAN]] Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma. | |||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | *[[Hydroxysteroid dehydrogenase|Hydroxysteroid dehydrogenase]] | ||
[[Category: | [[Category: 17-beta-estradiol 17-dehydrogenase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C.]] | [[Category: Arrowsmith, C.]] | ||
