2xzb: Difference between revisions

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[[Image:2xzb.png|left|200px]]
{{STRUCTURE_2xzb|  PDB=2xzb  |  SCENE=  }}  
{{STRUCTURE_2xzb|  PDB=2xzb  |  SCENE=  }}  
===Pig Gastric H,K-ATPase with bound BeF and SCH28080===
{{ABSTRACT_PUBMED_21224846}}


===Pig Gastric H,K-ATPase with bound BeF and SCH28080===
==Disease==
[[http://www.uniprot.org/uniprot/ATP4B_PIG ATP4B_PIG]] Note=Parietal cell autoantigen associated with autoimmune gastritis.


{{ABSTRACT_PUBMED_21224846}}
==Function==
[[http://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG]] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.


==About this Structure==
==About this Structure==
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==Reference==
==Reference==
<ref group="xtra">PMID:021224846</ref><references group="xtra"/>
<ref group="xtra">PMID:021224846</ref><references group="xtra"/><references/>
[[Category: Hydrogen/potassium-exchanging ATPase]]
[[Category: Hydrogen/potassium-exchanging ATPase]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]

Revision as of 02:01, 25 March 2013

Template:STRUCTURE 2xzb

Pig Gastric H,K-ATPase with bound BeF and SCH28080

Template:ABSTRACT PUBMED 21224846

Disease

[ATP4B_PIG] Note=Parietal cell autoantigen associated with autoimmune gastritis.

Function

[ATP4A_PIG] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.

About this Structure

2xzb is a 2 chain structure with sequence from Sus scrofa. Full crystallographic information is available from OCA.

See Also

Reference

  1. Abe K, Tani K, Fujiyoshi Y. Conformational rearrangement of gastric H(+),K(+)-ATPase induced by an acid suppressant. Nat Commun. 2011 Jan;2(1):155. PMID:21224846 doi:10.1038/ncomms1154

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