2pqk: Difference between revisions
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{{STRUCTURE_2pqk| PDB=2pqk | SCENE= }} | {{STRUCTURE_2pqk| PDB=2pqk | SCENE= }} | ||
===X-ray crystal structure of human Mcl-1 in complex with Bim BH3=== | ===X-ray crystal structure of human Mcl-1 in complex with Bim BH3=== | ||
{{ABSTRACT_PUBMED_20066663}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/MCL1_HUMAN MCL1_HUMAN]] Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.<ref>PMID:10766760</ref> | |||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Bcl-2|Bcl-2]] | *[[Bcl-2|Bcl-2]] | ||
==Reference== | |||
<ref group="xtra">PMID:020066663</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Bare, E.]] | [[Category: Bare, E.]] | ||
