1f6w: Difference between revisions
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{{STRUCTURE_1f6w| PDB=1f6w | SCENE= }} | {{STRUCTURE_1f6w| PDB=1f6w | SCENE= }} | ||
===STRUCTURE OF THE CATALYTIC DOMAIN OF HUMAN BILE SALT ACTIVATED LIPASE=== | |||
{{ABSTRACT_PUBMED_11045623}} | |||
== | ==Disease== | ||
[[http://www.uniprot.org/uniprot/CEL_HUMAN CEL_HUMAN]] Defects in CEL are a cause of maturity-onset diabetes of the young type 8 with exocrine dysfunction (MODY8) [MIM:[http://omim.org/entry/609812 609812]]; also known as diabetes and pancreatic exocrine dysfunction (DPED). MODY is a form of diabetes that is characterized by an autosomal dominant mode of inheritance, onset in childhood or early adulthood (usually before 25 years of age), a primary defect in insulin secretion and frequent insulin-independence at the beginning of the disease.<ref>PMID:16369531</ref> | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CEL_HUMAN CEL_HUMAN]] Catalyzes fat and vitamin absorption. Acts in concert with pancreatic lipase and colipase for the complete digestion of dietary triglycerides. | |||
==About this Structure== | ==About this Structure== | ||
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==See Also== | ==See Also== | ||
*[[Cholesterol esterase|Cholesterol esterase]] | |||
*[[Lipase|Lipase]] | *[[Lipase|Lipase]] | ||
==Reference== | ==Reference== | ||
<ref group="xtra">PMID:011045623</ref><references group="xtra"/> | <ref group="xtra">PMID:011045623</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Triacylglycerol lipase]] | [[Category: Triacylglycerol lipase]] | ||
